Retatrutide

• Works by activating three metabolic hormone receptors:
  • GLP-1: improves insulin release, reduces appetite.
  • GIP: enhances insulin sensitivity, supports energy balance.
  • Glucagon: increases energy expenditure and promotes fat burning.

This triple action gives Retatrutide a powerful metabolic effect on weight loss, blood sugar, and overall energy balance.

BENEFITS:

Extreme Weight Loss

• Up to 24% body weight reduction in trials (even higher than tirzepatide).
• Some participants lost 60+ pounds over 48–72 weeks.
• Among the most effective weight loss drugs ever tested.

 Improves Blood Sugar in Type 2 Diabetes

• Strong HbA1c reductions (1.8–2.2% or more).
• Supports glucose control across fasting and post-meal periods.

Increases Energy Expenditure

• Unlike semaglutide or tirzepatide, Retatrutide’s glucagon activation helps burn more calories.
• Enhances fat oxidation and reduces fat storage.

Improves Liver Health

• Shown to reduce liver fat in patients with NAFLD/NASH.
• May slow or reverse early liver damage (inflammation/fibrosis).

Enhances Cardiometabolic Markers

• Reduces:
  • Triglycerides
  • LDL cholesterol
  • Blood pressure
  • Inflammatory markers
• Improves insulin sensitivity.

Preserves Muscle Mass

• Similar to tirzepatide, early trials suggest lean mass retention during weight loss.
• Supports healthier body composition (fat loss > muscle loss).

Suppresses Appetite

• Stronger appetite suppression than GLP-1 or GLP-1/GIP drugs alone.
• Enhances satiety, reduces cravings and emotional eating.

Improves Quality of Life

• Participants reported:
  • Better energy
  • Greater mobility
  • Fewer obesity-related symptoms
  • Better mental and emotional health